New NIH Funding Opportunity Announcement to Support Health Care Systems Research Collaboratory Demonstration Projects


This FOA solicits applications to support Demonstration Projects that include an efficient, large-scale pragmatic clinical trial. Trials must be conducted across two or more health care systems (HCS) and must be conducted as part of the NIH HCS Research Collaboratory supported through the NIH Common Fund. Awards made through this FOA will initially support a one-year milestone-driven planning phase (UG3), with possible rapid transition to the second implementation phase (UH3) for a pragmatic trial Demonstration Project.

Access the full funding announcement at

View an NIH videocast answering questions about this RFA at


Important Due Dates for RFA-RM-16-019
Earliest submission date: May 2, 2017
Letter of intent due date: 30 days prior to application due date
Application due date: June 2, 2017